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主营类目:补充试剂
℡ 4000-520-616
℡ 4000-520-616
Complement Technology/C1s-Dpl/0.5 ml/vial/A304
产品编号:A304
市  场 价:¥3020.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$151.00
品      牌: Complement
公      司:Complement Technology, Inc.
公司分类:
Complement Technology/C1s-Dpl/0.5 ml/vial/A304
商品介绍

Product Description

C1s depleted serum (C1s-Dpl) is normal human serum depleted of C1s byimmunoaffinity chromatography. The product is tested for the absence ofC1s by functional assays for classical pathway activity and for C1sprotein by double immunodiffusion. C1s-Dpl is certified to possess afunctional alternative pathway for complement activation (Morgan, B.P.(2000); Dodds, A.W. and Sim, R.B. (1997)).

In serumC1s is present in its proenzyme form (Valet, G and Cooper N.R. (1974);Ziccardi, R.J. and Cooper N.R. (1976)). C1s enzyme is the activated formof C1s proenzyme. C1s is a subunit of the C1 complex which is the firstcomponent in the classical pathway of complement (See productdescription for C1 Cat# A098). C1s proenzyme is an inactive zymogenuntil C1 is activated. C1r is activated when C1 binds to and isactivated by antibodies bound to antigens (immune complexes) yieldingC1r enzyme, the first protease that initiates the cascade. C1r enzyme inthe C1 complex activates C1s proenzyme generating C1s enzyme. Afunctional classical pathway can be reconstituted by addition ofpurified C1s proenzyme (31 µg/mL) to the C1s-Dpl indicating that allother complement components necessary for classical pathway activationare present and active.

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品牌介绍

Complement Technology,Inc。(CompTech)致力于为生物医学研究界提供最高质量的补充试剂。CompTech的业主和员工在补充领域拥有超过80年的综合经验。我们是我们销售的补充试剂的原始制造商,我们努力成为最优质试剂的最低成本供应商。我们不断扩大我们生产的试剂系列,以满足不断变化的研究需求。我们欢迎您提供所需新试剂的建议。

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